Research Projects | ImmuneMed

Research Projects

Research Projects

정부과제 수행실적 정보
No. Name of the Program
(Enforcement Departments/ Agencies)
Name of
the Project
Name of the Project
Project
Completion
Period
Summary
19 Ministry of SMEs and Startups(MSS). Development of Leptospira-Antigen-Antibody Diagnostic Kit
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Ministry of SMEs and Startups(MSS).
  • Name of the Project :
    Development of Leptospira-Antigen-Antibody Diagnostic Kit
  • Project Completion Period :
    2018.09.03.~2020.09.02
  • Summary :
    It is a diagnostic kit that can detect leptospirosis infection by detecting leptospira antigen for the first time in the word as the on-site rapid qualitative diagnostic kit. Low concentrations of leptospira can be detected by developing specific monoclonal antibodies to leptospira cells and dripping a small amount of blood without sample pre-treatment. Also, the kit can detect IgM antibodies to leptospira, which can predict the progression of the disease.
2018.09.03.
~2020.09.02
It is a diagnostic kit that can detect leptospirosis infection by detecting leptospira antigen for the first time in the word as the on-site rapid qualitative diagnostic kit. Low concentrations of leptospira can be detected by developing specific monoclonal antibodies to leptospira cells and dripping a small amount of blood without sample pre-treatment. Also, the kit can detect IgM antibodies to leptospira, which can predict the progression of the disease.
18 Research project for technology application for civilian military technology cooperation (Ministry of Commerce, Industry and Energy). Development of POCT Diagnostic System for Typhoid Fever and Paratyphoid Fever.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Research project for technology application for civilian military technology cooperation (Ministry of Commerce, Industry and Energy).
  • Name of the Project :
    Development of POCT Diagnostic System for Typhoid Fever and Paratyphoid Fever.
  • Project Completion Period :
    2018.07.01.~2020.12.31
  • Summary :
    It is the world’s first simultaneous diagnosis kit of typhoid and paratyphoid with the principle of immunochromatography applied. It isolates and purifies typhoid and paratyphoid specific antigens, and diagnoses infectious diseases caused by typhoid and paratyphoid bacteria among more than 2,500 salmonella serotypes with 3㎕ of blood, not fecal, which enables control, prevention, and epidemiological investigation of infectious diseases by the national defense system by distinguishing typhoid and paratyphoid at the time of salmonella infection.
2018.07.01.
~2020.12.31
It is the world’s first simultaneous diagnosis kit of typhoid and paratyphoid with the principle of immunochromatography applied. It isolates and purifies typhoid and paratyphoid specific antigens, and diagnoses infectious diseases caused by typhoid and paratyphoid bacteria among more than 2,500 salmonella serotypes with 3㎕ of blood, not fecal, which enables control, prevention, and epidemiological investigation of infectious diseases by the national defense system by distinguishing typhoid and paratyphoid at the time of salmonella infection.
17 Business development technology development project (Ministry of Commerce, Industry and Energy). Develop new anti-viral drugs to treat various viral infectious diseases.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Business development technology development project (Ministry of Commerce, Industry and Energy).
  • Name of the Project :
    Develop new anti-viral drugs to treat various viral infectious diseases.
  • Project Completion Period :
    2017.09.01.~2019.12.31
  • Summary :
    It is the only RDT that can diagnose dengue hemorrhagic fever quickly, accurately, and simply. It can detect IgM and IgG per dengue virus (DV) 1, 2, 3, and 4 serotypes, respectively, which lowers the mortality rate of dengue virus infection by predicting whether infection progress to either dengue fever or dengue hemorrhagic fever.
2017.09.01.
~2019.12.31
It is the only RDT that can diagnose dengue hemorrhagic fever quickly, accurately, and simply. It can detect IgM and IgG per dengue virus (DV) 1, 2, 3, and 4 serotypes, respectively, which lowers the mortality rate of dengue virus infection by predicting whether infection progress to either dengue fever or dengue hemorrhagic fever.
16 Healthcare Research and Development Project (Medical Device Technology Development Project, Ministry of Health and Welfare). Performance evaluation of hemorrhagic fever diagnosis kit after nephrotic syndrome.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Healthcare Research and Development Project (Medical Device Technology Development Project, Ministry of Health and Welfare).
  • Name of the Project :
    Performance evaluation of hemorrhagic fever diagnosis kit after nephrotic syndrome.
  • Project Completion Period :
    2016.07.01.~2017.12.31
  • Summary :
    Studies on HBV therapeutics, in vitro and in vivo validation: The validation, mechanism studies, 13-week GLP toxicity study (rats and beagle dogs), phase 1 clinical study IND approval, and in vivo validation of the woodchuck model infected with acute and chronic woodchuck hepatitis virus (WHV)
2016.07.01.
~2017.12.31
Studies on HBV therapeutics, in vitro and in vivo validation: The validation, mechanism studies, 13-week GLP toxicity study (rats and beagle dogs), phase 1 clinical study IND approval, and in vivo validation of the woodchuck model infected with acute and chronic woodchuck hepatitis virus (WHV)
15 Health & Medical Research & Development Project (Swine Influenza Bomber Project). Performance evaluation of hemorrhagic fever diagnosis kit after nephrotic syndrome.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Health & Medical Research & Development Project (Swine Influenza Bomber Project).
  • Name of the Project :
    Performance evaluation of hemorrhagic fever diagnosis kit after nephrotic syndrome.
  • Project Completion Period :
    2015.11.01.~2017.10.31
  • Summary :
    The clinical efficacy of the nephrotic hemorrhagic fever diagnosis kit currently on sale has been verified through the post-marketing survey held at Chuncheon Sacred Heart Hospital of Hallym University, a clinical evaluation institution of in vitro diagnostic medical devices and the results were published in an SCI level international journal.
2015.11.01.
~2017.10.31
The clinical efficacy of the nephrotic hemorrhagic fever diagnosis kit currently on sale has been verified through the post-marketing survey held at Chuncheon Sacred Heart Hospital of Hallym University, a clinical evaluation institution of in vitro diagnostic medical devices and the results were published in an SCI level international journal.
14 Research project for civil / military technology application (Ministry of Commerce, Industry and Energy, Defense Business Administration). Organophosphate poisoning measurement and BuChE detection kit development.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Research project for civil / military technology application (Ministry of Commerce, Industry and Energy, Defense Business Administration).
  • Name of the Project :
    Organophosphate poisoning measurement and BuChE detection kit development.
  • Project Completion Period :
    2015.05.08.~2017.05.07
  • Summary :
    It is the only diagnostic kit that can detect sarin, soman, and Vx organophosphorus toxic substances among the nervous system toxicants used as killer gas during the war, pesticides, or herbicides. The kit determines the exposure and extent of poison gas using a drop of blood when a person inhaled colorless, tasteless, or odorless poison gas leaked into the air to allow treatment with an appropriate antidote for the type of poison gas.
2015.05.08.
~2017.05.07
It is the only diagnostic kit that can detect sarin, soman, and Vx organophosphorus toxic substances among the nervous system toxicants used as killer gas during the war, pesticides, or herbicides. The kit determines the exposure and extent of poison gas using a drop of blood when a person inhaled colorless, tasteless, or odorless poison gas leaked into the air to allow treatment with an appropriate antidote for the type of poison gas.
13 New Drug Development Project (Bipartite New Drug Development Project). Development of a novel anti-viral therapeutic agent that selectively acts on virus-infected cells.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    New Drug Development Project (Bipartite New Drug Development Project).
  • Name of the Project :
    Development of a novel anti-viral therapeutic agent that selectively acts on virus-infected cells.
  • Project Completion Period :
    2014.09.01.~2017.02.28
  • Summary :
    Production of hzVSF-v12 and hzVSF-v13, derivation of candidate materials through immunogenicity study, hzVSF-v13 production and cell line establishment, studies on HCV and HBV mechanisms, validation of HCV and HBV animal models: Validation of hzVSF-v13 after infecting human liver cell transplanted SCID/Alb-uPA mice with each virus, Validation of hzVSF-v13 on Ebola virus:
2014.09.01.
~2017.02.28
Production of hzVSF-v12 and hzVSF-v13, derivation of candidate materials through immunogenicity study, hzVSF-v13 production and cell line establishment, studies on HCV and HBV mechanisms, validation of HCV and HBV animal models: Validation of hzVSF-v13 after infecting human liver cell transplanted SCID/Alb-uPA mice with each virus, Validation of hzVSF-v13 on Ebola virus:
12 Research project for technology application for civilian military technology cooperation (Ministry of Commerce, Industry and Energy). Development of Tsutsugamushi diagnostic kit for outdoor use.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Research project for technology application for civilian military technology cooperation (Ministry of Commerce, Industry and Energy).
  • Name of the Project :
    Development of Tsutsugamushi diagnostic kit for outdoor use.
  • Project Completion Period :
    2014.06.13.~2016.06.12
  • Summary :
    It is a diagnostic kit for scrub typhus that can be used in vitro and in vivo (mice) group. Reflecting the characteristics of soldiers who are involved with a lot of outdoor activities, the kit has applied the cut-off differentiation optimized for military use and the lancet for emergency use to enable the diagnosis during outdoor and field training unlike the diagnostic criteria for civilians.
2014.06.13.
~2016.06.12
It is a diagnostic kit for scrub typhus that can be used in vitro and in vivo (mice) group. Reflecting the characteristics of soldiers who are involved with a lot of outdoor activities, the kit has applied the cut-off differentiation optimized for military use and the lancet for emergency use to enable the diagnosis during outdoor and field training unlike the diagnostic criteria for civilians.
11 Combined Technology Development Project (Small and Medium Business Administration). Development of diagnostic tool for Tsutsugamushi disease for global export including Southeast Asia.
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Combined Technology Development Project (Small and Medium Business Administration).
  • Name of the Project :
    Development of diagnostic tool for Tsutsugamushi disease for global export including Southeast Asia.
  • Project Completion Period :
    2013.12.01.~2015.11.30
  • Summary :
    Since scrub typhus is a disease that occurs frequently in Southeast Asia including Korea, the kit has applied the diagnostic standards established for Korea and each country of the endemic region. The kit is a small portable diagnostic device that can quantify the antibody tier using fluorescence to detect a small quantity of antibodies.
2013.12.01.
~2015.11.30
Since scrub typhus is a disease that occurs frequently in Southeast Asia including Korea, the kit has applied the diagnostic standards established for Korea and each country of the endemic region. The kit is a small portable diagnostic device that can quantify the antibody tier using fluorescence to detect a small quantity of antibodies.
10 Project for Regional Innovative Center (Center for efficacy assessment and development of functional foods and drugs) Clinical Study and KFDA Approval of Scrub Typhus Diagnostic Kit
  • Name of the Program
    (Enforcement Departments/ Agencies) :
    Project for Regional Innovative Center (Center for efficacy assessment and development of functional foods and drugs)
  • Name of the Project :
    Clinical Study and KFDA Approval of Scrub Typhus Diagnostic Kit
  • Project Completion Period :
    2012.03.01.~2013.02.28
  • Summary :
    This is a confirmatory clinical study of the scrub typhus diagnostic kit to demonstrate the stability and validity of the technical documentation for the product marketing authorization review, which is required for sales. The clinical performance was evaluated by Chuncheon Sacred Heart Hospital of Hallym University and the analytical performance by an evaluation institution such as the Korea Testing Certification (KTC).
2012.03.01.
~2013.02.28
This is a confirmatory clinical study of the scrub typhus diagnostic kit to demonstrate the stability and validity of the technical documentation for the product marketing authorization review, which is required for sales. The clinical performance was evaluated by Chuncheon Sacred Heart Hospital of Hallym University and the analytical performance by an evaluation institution such as the Korea Testing Certification (KTC).