Research Projects
| No. | Name of Program (Enforcement Departments/ Agencies) |
Name of ProjectName of Project |
Project Completion Period |
Summary |
|---|---|---|---|---|
| 22 | Technology development project for infectious disease prevention and treatment (vaccine commercialization) / Ministry of Health and Welfare |
Non-clinical testing and efficacy evaluation of dengue vaccine with improved specificity through recombination of dengue virus epidermal antigens
|
2021.01.21 ~2022.12.31 |
It is aimed to secure vaccines that combine four types of dengue virus serum proteins with immunostrengthening agents, resulting in inducing high immunogenicity; It is centered on proving their efficacy against dengue viruses and safety against ADE and toxicity. |
| 21 | Center for Medical Technology Commercialization Support / Ministry of Health and Welfare |
Clinical evaluation for domestic and overseas approval of IMMUNEMED COVID-19 IgM/IgG RAPID
|
2020.11.05 ~2021.05.04 |
In vitro diagnostic medical devices diagnosing coronavirus are evaluated by qualifying IgM and IgG antibodies against SARS-CoV-2 with Immunochromatography assay in human blood. |
| 20 | Technology development project for infectious disease prevention and treatment / Ministry of Health and Welfare |
Phase 2 clinical evaluation of PoC for developing treatment of chronic hepatitis B utilizing hzVSF
|
2020.04.23 ~2022.12.31 |
After completing the phase 1 clinical trial to apply the humanized Virus Suppressing Factor (hzVSF) currently under development as a treatment for chronic hepatitis B, it is scheduled to conduct long-term GLP toxicity and clinical phase 2a test in order to receive approval of IND for phase 2b clinical trial. |
| 19 | Ministry of SMEs and Startups / MSS |
Development of Leptospira-Antigen-Antibody Diagnostic Kit
|
2018.09.03 ~2020.09.02 |
It is a diagnostic kit that can detect leptospirosis infection by detecting leptospira antigen for the first time in the word as the on-site rapid qualitative diagnostic kit. Low concentrations of leptospira can be detected by developing specific monoclonal antibodies to leptospira cells and dripping a small amount of blood without sample pre-treatment. Also, the kit can detect IgM antibodies to leptospira, which can predict the progression of the disease. |
| 18 | Research project for technology application for civilian military technology cooperation / Ministry of Commerce, Industry and Energy |
Development of POCT Diagnostic System for Typhoid Fever and Paratyphoid Fever.
|
2018.07.01 ~2021.06.30 |
It is the world’s first simultaneous diagnosis kit of typhoid and paratyphoid with the principle of immunochromatography applied. It isolates and purifies typhoid and paratyphoid specific antigens, and diagnoses infectious diseases caused by typhoid and paratyphoid bacteria among more than 2,500 salmonella serotypes with 3㎕ of blood, not fecal, which enables control, prevention, and epidemiological investigation of infectious diseases by the national defense system by distinguishing typhoid and paratyphoid at the time of salmonella infection. |
| 17 | Business development technology development project / Ministry of Commerce, Industry and Energy |
Develop new anti-viral drugs to treat various viral infectious diseases.
|
2017.09.01 ~2019.12.31 |
It is the only RDT that can diagnose dengue hemorrhagic fever quickly, accurately, and simply. It can detect IgM and IgG per dengue virus (DV) 1, 2, 3, and 4 serotypes, respectively, which lowers the mortality rate of dengue virus infection by predicting whether infection progress to either dengue fever or dengue hemorrhagic fever. |
| 16 | Healthcare Research and Development Project / Medical Device Technology Development Project, Ministry of Health and Welfare |
Performance evaluation of hemorrhagic fever diagnosis kit after nephrotic syndrome.
|
2016.07.01 ~2017.12.31 |
Studies on HBV therapeutics, in vitro and in vivo validation: The validation, mechanism studies, 13-week GLP toxicity study (rats and beagle dogs), phase 1 clinical study IND approval, and in vivo validation of the woodchuck model infected with acute and chronic woodchuck hepatitis virus (WHV). |
| 15 | Health & Medical Research & Development Project / Swine Influenza Bomber Project |
Performance evaluation of hemorrhagic fever diagnosis kit after nephrotic syndrome.
|
2015.11.01 ~2017.10.31 |
The clinical efficacy of the nephrotic hemorrhagic fever diagnosis kit currently on sale has been verified through the post-marketing survey held at Chuncheon Sacred Heart Hospital of Hallym University, a clinical evaluation institution of in vitro diagnostic medical devices and the results were published in an SCI level international journal. |
| 14 | Research project for civil (military technology application) / Ministry of Commerce, Industry and Energy, Defense Business Administration |
Organophosphate poisoning measurement and BuChE detection kit development.
|
2015.05.08 ~2017.05.07 |
It is the only diagnostic kit that can detect sarin, soman, and Vx organophosphorus toxic substances among the nervous system toxicants used as killer gas during the war, pesticides, or herbicides. The kit determines the exposure and extent of poison gas using a drop of blood when a person inhaled colorless, tasteless, or odorless poison gas leaked into the air to allow treatment with an appropriate antidote for the type of poison gas. |
| 13 | New Drug Development Project / Bipartite New Drug Development Project |
Development of a novel anti-viral therapeutic agent that selectively acts on virus-infected cells.
|
2014.09.01 ~2017.02.28 |
Production of hzVSF-v12 and hzVSF-v13, derivation of candidate materials through immunogenicity study, hzVSF-v13 production and cell line establishment, studies on HCV and HBV mechanisms, validation of HCV and HBV animal models: Validation of hzVSF-v13 after infecting human liver cell transplanted SCID/Alb-uPA mice with each virus, Validation of hzVSF-v13 on Ebola virus. |